The analgesic properties of codeine are speculated to originate from its conversion to morphine, although the correct mechanism of analgesic motion remains mysterious.
Stay away from the use of acetaminophen and codeine phosphate tablets in adolescents 12 to eighteen many years of age who produce other danger things which could boost their sensitivity to the respiratory depressant results of codeine unless the benefits outweigh the dangers.
e., several copies from the gene for cytochrome P450 isoenzyme 2D6 or superior morphine concentrations). Kids with snooze apnea may very well be significantly sensitive for the respiratory depressant outcomes of codeine. As a result of threat of lifetime-threatening respiratory despair and death:
When using acetaminophen and codeine phosphate tablets: Don't adjust your dose. Consider acetaminophen and codeine phosphate tablets exactly as prescribed by your Health care provider. Use the bottom dose achievable for your shortest time wanted. For acute (quick-term) pain, you may only really need to just take acetaminophen and codeine phosphate tablets for a few days.
If anyone has overdosed and has serious symptoms for instance passing out or problems respiratory, give them naloxone if available, then phone 911. If the person is awake and it has no indicators, phone a poison Command Heart immediately.
Misuse would be the intentional use, for therapeutic needs, of the drug by someone in a method other than prescribed by a healthcare supplier or for whom it was not prescribed.
Assess Every affected person's chance previous to prescribing and observe all patients often for the development of those behaviors or ailments.
An opioid soreness medicine that will put you in danger for overdose and Demise. Even if you acquire your dose appropriately as prescribed, you're in danger for opioid habit, abuse, and misuse that can lead to Demise.
Will not read more maintain leftover opioid medication. Only one dose can cause death in an individual working with this medicine accidentally or improperly.
It's safer to underestimate a individual’s 24-hour acetaminophen and codeine phosphate tablets dosage than to overestimate the 24-hour acetaminophen and codeine phosphate tablets dosage and click here take care of an adverse reaction on account of overdose.
Gals of kid bearing potential need to realize that read more prolonged use throughout pregnancy can result in neonatal read more opioid withdrawal syndrome Which prompt recognition and procedure might here be necessary.
Use with caution; get started with lower doses or with for a longer time dosing intervals and titrate bit by bit whilst meticulously monitoring for Unintended effects.
Misuse and abuse of acetaminophen and codeine phosphate tablets boosts risk of overdose, which may cause central anxious method and respiratory melancholy, hypotension, seizures, and Dying. The danger is greater with concurrent abuse of acetaminophen and codeine phosphate tablets with alcohol and also other CNS depressants.
There may be variability during the opioid analgesic dose and period necessary to adequately handle pain thanks both equally to the reason for ache and to person affected person elements.